Mass spectroscopy

Mass spectrometry fundamentals

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An interactive exploration of mass spectrometry fundamentals from familiarisation with how mass spectrometers work, interoperation of fragmentation patterns, to analysis of spectra and apply understanding of ionisation techniques to determine molecular structures.

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Learning outcomes

identify the order of key steps of running a mass spectrometer.
summarise concepts about fragmentation and separation of particles during mass spectrometry.
identify fragment ions and their lost radical using mass to charge ratio \( (\text{m/z}) \).
interpret a mass spectrum by identifying \( (\text{m/z}) \) of molecular ion, base peak and potential radical loss.

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Skills

Concepts, Principles and Theories

How a mass spectrometer works to achieve fragmentation of a molecule
How to identify lost radicals and their effect on mass spectrometry data

Using Instruments and Equipment

What the required steps are to run a mass spectrometer

Interpreting and Analysing Data

How to identify the structure of a fragment ion based on its m/z value
How to determine m/z value of the base peak from a spectrum
How to determine m/z value for molecular ion peak

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Student, University of Glasgow

“It’s just at that point where it is not telling you the answer but it’s helping you get there. If I get the feedback a week later, I’m too busy working on the next lab report.”

Details

Degrees

Chemistry

Forensic science

Foundation science

Discipline

Analytical chemistry

Topic

Mass spectroscopy

Purchase option

The Smart Worksheet Library

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