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Pharmacology

Aorta organ bath

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Explore an organ bath experiment on aorta tissue. Calculate a range of drug doses and combinations, determine percentage response from experimental data, and select options such as linear or log scale for plotting the dose-response curves.

Learning outcomes

  • calculate final bath concentration (FBC).
  • determine \(\%\) response for each run with a particular drug.
  • construct a dose-response curve.
  • categorise experimental findings back to drug-receptor interactions within the aorta.
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Skills

Manipulating and Presenting Data

  • Construct dose-response curves by selecting appropriate variables for the x and y axes
  • Evaluate and apply linear or logarithmic scales to optimally present pharmacological data

Interpreting and Analysing Data

  • Calculate final bath concentrations (FBC) and tissue percent responses from raw experimental data
  • Interpret shifts in dose-response curves to deduce the physiological effects of various drug combinations

Concepts, Principles and Theories

  • Categorise experimental findings to explain drug-receptor interactions within the aorta
  • Apply pharmacological principles to identify the roles of agonists, competitive antagonists, and enzyme inhibitors

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Dr. Alexandra Moores
University of Kent

"The Smart Worksheets are extremely useful to see the overall understanding and application of theories that we expected students to be able to use. Feedback is clear and accessible, enabling students to gain a deeper understanding of the topic they are studying and aiding in their success.”

Details

Degrees

Biological science
Biomedical science
Pharmaceutical science

Discipline

Health science

Topic

Pharmacology

Purchase option

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