Genetics

Gene regulation: the lac operon

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Delve into the molecular biology of the lac operon, what it does and why, exploring the biochemistry under different biological growth conditions. Build a growth curve and use the data to justify the type of lac operon mutation present in each bacterial strain and the reasons why.

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Learning outcomes

Describe the structure and function of the different elements of the lac operon.
Apply knowledge of the lac operon to specific species and culture conditions.
Create and interpret graphs by defining parameters and analyse sugar utilisation and growth data.
Justify how growth behaviour and metabolite utilisation relates to the molecular mechanisms of the lac operon system.

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Skills

Manipulating and Presenting Data

How to plot graphs showing cell mass and sugar concentration

Interpreting and Analysing Data

Defining cell molecular states and activities based on growth conditions
Justifying a molecular phenotype based on graphical data

Concepts, Principles and Theories

Identifying the different parts of the lac operon
Describing the impact of different sugars on the regulation of the lac operon and the relative levels of transcription and repression

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Prof. Nicholas Harmer

University of Exeter

“We would like to bring Smart Worksheets into more areas because they're transformative in terms of getting students to really get to grips with problems and to upskill themselves numerically.”

Details

Degrees

Biological science

Biomedical science

Foundation science

Pharmaceutical science

Modules

Molecular biology

Topic

Genetics

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The Smart Worksheet Library

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