Haematology and transfusion science

Haematopoiesis

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An introduction to the location, processes and regulation of blood cell development. Explore the morphology of cell developmental stages and how the stem cell niche regulate haemotopoesis. Learn about how cell surface markers change according to cell lineage and apply understanding of haematopoesis to reference ranges, bone marrow aspirates and bone marrow trephine.

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Learning outcomes

Apply knowledge of the process of haematopoiesis relative to age, normal reference range and bone marrow cellularity.
Analyse and interpret micrographs of red and white cell key developmental stages.
Demonstrate knowledge of factors affecting the stem cell niche, haematopoiesis regulation and neoplasm.
Evaluate the clinical significance of bone marrow trephine and bone marrow aspirates.
Apply critical thinking to evaluate blood counts and bone marrow aspirates.

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Skills

Interpreting and Analysing Data

How to accurately identify normal and abnormal morphologies of blood cells from blood films, bone marrow trephine and aspirates
How to correlate morphological features with expected reference ranges

Concepts, Principles and Theories

Recall and consolidate knowledge of haematopoiesis to understand the principles of reference ranges and the impact of dysregulation on neoplasms

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Prof. Nicky King

University of Exeter

"The great thing about Smart Worksheets is that they tell you at every point whether you’ve got it right or wrong, what might be wrong and how you might go about changing it. The students found that really valuable. In their exam, we found that the average mark in the maths questions rose from 59% to 79%, which made a really big difference to the student outcome.”

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Degrees

Biomedical science