Haematology and transfusion science

Haemostasis

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This is a comprehensive overview of haemostasis, covering the traditional cascade model of coagulation, primary haemostasis in response to vascular injury, secondary haemostasis, and the coagulation factors needed to form a stable fibrin clot. Exploration of these three key areas in a diagnostic setting is underpinned by the importance of internal quality control measures and evaluating data that shows variation from the normally expected parameters for clotting. This Smart Worksheet is a combination of two others: 'Haemostasis and quality control' and 'Primary and secondary haemostasis'.

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Learning outcomes

Analyse and interpret quality control (QC) data.
Apply knowledge of quality control checks and take appropriate action as needed depending on QC results.
Demonstrate the ability to identify characteristic shifts in clot curves and first and second derivatives.
Evaluate the clinical significance of unexpected results to identify disease states.
Apply critical thinking and decision-making skills in appropriate sequential testing based on results and clinical history.

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Skills

Concepts, Principles and Theories

Recall knowledge of primary and secondary haemostasis and apply this to the evaluation of PFA data and clot curve analysis
Utilise critical thinking and evaluation of complex case study data

Interpreting and Analysing Data

How to use internal qulaity control data to determine quality and validity of data

Manipulating and Presenting Data

How to carry out calculations using aPTT and PT data sets to generate Levey-Jennings plots and compare against QC parameters

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Dr. Alexandra Moores

University of Kent

"The Smart Worksheets are extremely useful to see the overall understanding and application of theories that we expected students to be able to use. Feedback is clear and accessible, enabling students to gain a deeper understanding of the topic they are studying and aiding in their success.”

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Degrees

Biomedical science