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Clinical immunology

Internal quality control and systemic lupus erythematosus diagnosis

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Explore the need for specific diagnostic tests to ensure accuracy of diagnosis for SLE, such as antinuclear antibody and dsDNA testing. Understand the need for internal quality control measures to ensure accurate diagnostic testing.

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Learning outcomes

  • Apply knowledge of systemic lupus erythematosus signs and symptoms.
  • Analyse and interpret anti-nuclear antibody indirect immunofluorescence results.
  • Demonstrate understanding of internal quality control measures for double stranded DNA testing and its application in diagnostic testing.
  • Evaluate the clinical significance of double stranded DNA antibody fluorescence patterns in diagnosing systemic lupus erythematosus.
  • Critically analyse the process of differential diagnosis and diagnostic evaluation for systemic lupus erythematosus.
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Skills

Concepts, Principles and Theories

  • Applying knowledge of key diagnostic tests to identfy indicators of systemic lupus erythematosus.

Interpreting and Analysing Data

  • Interpreting images of anti-nuclear antibody testing and indirect immunofluorescence performed on Crithidia luciliae.

Manipulating and Presenting Data

  • Determining internal quality control internal ranges, constructing Levey-Jennings plots.
  • Applying Westgard rules to establish the validity of diagnostic results.

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Dr. Alexandra Moores
University of Kent

"The Smart Worksheets are extremely useful to see the overall understanding and application of theories that we expected students to be able to use. Feedback is clear and accessible, enabling students to gain a deeper understanding of the topic they are studying and aiding in their success.”

Details

Degrees

Biomedical science

Modules

Clinical biomedical science

Topic

Clinical immunology

Purchase option

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Biomedical science
autoimmune disease
disease
clinical diagnostics
Antibodies
quality control
Levey-Jennings
Clinical biomedical science
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