< Back to the full list

Clinical biochemistry

Therapeutic drug monitoring and steady state

No items found.

Revisit the principles of drug elimination, metabolism and pharmacokinetics, expanding and applying them in the context of therapeutic drug monitoring. Explore the concept of steady state and apply critical calculations to a clinical scenario to ensure accurate drug concentration maintenance within a therapeutic window.

Learning outcomes

  • Demonstrate an understanding of the mathematical concepts of pharmacokinetics and apply them to calculate the key variables.
  • Assess the mathematical concepts of steady state and use them to calculate the key variables.
  • Apply pharmacokinetic concepts to a novel clinical scenario, then analyse and interpret complex data to determine the therapeutic window.
No items found.
chevron_left
chevron_right

Skills

Manipulating and Presenting Data

  • Calculate the individual and total area under the curve (AUC) for some pharmacokinetic elimination data
  • Extrapolate the AUC to infinity and use this to calculate drug bioavailability
  • Calculate the point at which steady state is achieved for a specific drug regime
  • Calculate all the pharmacokinetic parameters for a patient in a clinical scenario

Interpreting and Analysing Data

  • Explore how apparent volume of distribution is impacted by weight

Concepts, Principles and Theories

  • Explore how the equation of a line relates to pharmacokinetic measurements
  • Define how drugs are modified and characterise the principles of steady state

Learn more about our approach to skills
Dr Linda Walsh, Senior Lecturer, Glasgow Caledonian University and IBMS Council Member

“Clinical biochemistry is a complex subject area which requires applying fundamental knowledge in a variety of clinical areas. Students often struggle to connect the pathways required to integrate their knowledge, therefore using patient case studies allows the knowledge they have to be applied in real-life scenarios. This makes the reliance on memorising and recall less necessary.”

Details

Subject areas

Biomedical science

Discipline

Clinical biomedical science

Topic

Clinical biochemistry

Purchase option

The Smart Worksheet Library

Related products

What are LabSims?

Our virtual lab simulations enhance student learning by building confidence in practical skills.
  • Enhance student skills and accelerate learning with multiple opportunities to practise
  • Boost confidence and competency with enhanced support and personalised feedback
  • Engage and motivate with enjoyable, challenging learning experiences
LabSim product page

What are Smart Worksheets?

Online, autograded assessment tool for advanced data analysis and calculation practice
  • Improve the student experience of assessment with immediate, targeted feedback
  • Save academic time by minimising repetitive marking for staff
  • Gain immediate insight into student progress with individual performance data
Smart Worksheets product page

Integrate with your LMS

Our products integrate with all major learning platforms, including Canvas, Blackboard, Moodle, Sakai and Brightspace or without any LMS using our LearnSci Direct Platform.
Learn more about LearnSci Direct.
No items found.

See how our resources can enhance your student experiences

  • Try our resources for free
  • Get a live demonstration of our products
  • Become a partner and join our community
  • Talk to our team of experts
Request a demo
Image of a smiling student with a microscope