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Clinical genetics

Monogenic disorders and inheritance

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Explore how monogenic disorders are inherited and predicted through the use of Punnet squares, dihybrid crosses and generational pedigree analysis. Navigate the differences between sex-linked, recessive and dominant alleles and the impact they have on inheritance patterns.

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Learning outcomes

  • Identify inheritance patterns based on clinical presentations.
  • Define genetic conventions and recall the principles of underlying mechanisms and disorders.
  • Solve Punnet squares and inheritance patterns to predict the probabilities of genotypes and phenotypes.
  • Deduce patterns from pedigrees and propose explanations for inheritance observations.
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Skills

Manipulating and Presenting Data

  • Solve Punnet squares and use them to predict the probabilities of clinical genotypes and phenotypes

Interpreting and Analysing Data

  • Identify and solve inheritance patterns and Punnet squares
  • Deduce various patterns from pedigrees in order to propose logical explanations for inheritance observations

Concepts, Principles and Theories

  • Define genetic conventions and propose genetic conditions that matches the inheritance pattern of a Pedigree

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Details

Subject areas

Biomedical science

Discipline

Clinical biomedical science

Topic

Clinical genetics

Purchase option

The Smart Worksheet Library

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Biomedical science
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Clinical biomedical science
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